In chronic autoimmune conditions such as myasthenia gravis (MG), immunosuppression—usually long-term—is often necessary. The mechanisms of action of immunosuppressant drugs in MG fall into three main categories: inhibition of the cell cycle (azathioprine, cyclophosphamide, methotrexate and mycophenolate mofetil), immunosuppression of T cells (steroids, ciclosporin and tacrolimus), and B-cell depletion (rituximab).
This interesting review article is worth reading.
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Immune suppression in Myasthenia
June 6, 2008
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