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Constipation

December 29, 2008

All you need to know about constipation is here..


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Skin signs in DM

December 16, 2008

Patients with type 2 diabetes more often develop skin infections, whereas those with type 1 more often have autoimmune-related lesions.Read more..


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Influenza- update

The Cleveland Clinic Journal of Medicine has a very helpful update in its December issue. Read more..


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Arthritis

Most Common Causes Of Arthritis In Small Joints Of The Hand
1. Rheumatoid arthritis (affects PIP, MCP, wrist — spares DIP and 1st MCP).

2. SLE (Jaccoud’s arthropathy: reducible, non-erosive joint deformities with a preservation of hand function).

3. Osteoarthritis (Bouchard and Herberden nodules on PIP and DIP respectively).

4. Gout (esp. chronic gouty polyarthritis).

5. Psoriatic arthritis (affects DIP and other joints of the hand).

6. Septic

7. Traumatic


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Colonoscopy and Cancer Mortality.

Colonoscopy is the “gold standard” for evaluation of the colon. Now, a new study published in Annals of Internal Medicine finds colonoscopy may not be as effective as previously believed. Read this editorial.. The Original article can be read here..



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ACCOMPLISH- another Hypertension trial

Still we are not sure what is the best combination treatment for hypertension. This study looked at ACE plus Ca blocker versus ACE plus Diuretic and looked at cardiovascluar end points. You can be sure which was better. after 36 months ARR was only 2.2% Read yourself..


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PCOS - Newer therapies

Treatment of PCOS has moved on from clomid in the eighties to metformin. Newer drugs like Glitazones have been tried. Combination of Metformin with Exanetide is an interesting option that has been reported recently..Read more



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WPW

December 12, 2008

An ECG of a 59-year-old woman with known Wolff-Parkinson-White (WPW) syndrome is shown below. The delta (Δ) waves are small, but definite. This patient, like many patients with WPW syndrome, often does not have them at all times. The PR intervals are not short (ie, <120 ms), usually one of the diagnostic features of WPW. However, the Δ wave is the key feature and the PR interval here suggests a delay in the normal A-V conduction, sometimes called “sick Kent syndrome.” The WPW QRS is a fusion beat between the accessory pathway and the normal A-V pathway.




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Movement disorders Emergencies

December 2, 2008

Movement disorder emergencies in the elderly—such as rigidity, dystonia, hyperkinetic movements, and psychiatric disturbances—are challenging to manage. Many cases are iatrogenic. In theory, some cases could be avoided by anticipating them and by avoiding polypharmacy and potentially dangerous drug interactions.Read more..


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Black Hairy Tongue


Black hairy tongue, also known as lingua villosa nigra, is a painless, benign disorder caused by defective desquamation and reactive hypertrophy of the filiform papillae of the tongue. The hairy appearance is due to elongation of keratinized filiform papillae, which may have different colors, varying from white to yellowish brown to black depending on extrinsic factors (eg, tobacco, coffee, tea, food) and intrinsic factors (ie, chromogenic organisms in normal flora).


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HBV - Natural History






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Primary Biliary Cirrhosis- Review

Primary biliary cirrhosis (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune etiology characterized by injury of the intrahepatic bile ducts that may eventually lead to liver failure. Affected individuals are usually in their fifth to seventh decades of life at time of diagnosis, and 90% are women.readmore>..


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