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Is it safe to give thrombolytics to patients already taking antiplatelets?

April 6, 2008

Prior use of antiplatelet (AP) drugs increases the risk of symptomatic intracerebral hemorrhage (SICH) and influences functional outcome in patients with ischemic stroke treated with intravenous thrombolysis.This is a single center prospective cohort study published in Archives in Neurology.
Conclusion Despite a higher incidence of SICH, the net benefit of intravenous tissue plasminogen activator therapy for acute ischemic stroke was greater in patients using AP drugs.

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