Current guidelines for ischaemic stroke stroke do not recommend emergency anti hypertensive therapy until SB 220 or DB 120 unless TPA is given. The guideline for hemorrhagic stroke allow a moderately more aggressive approach to blood pressure lowering depending on the clinician’s estimate or the actual measurement of intracranial pressure.
Results from a small study called CHIPPS presented at the American Stroke Association's (ASA's) International Stroke Conference 2008 demonstrated that immediate antihypertensive treatment targeted to a systolic blood pressure of 145 to 155 mm Hg or a drop in systolic blood pressure of 15 mm resulted in improved stroke outcomes at 3 months.
This small study should not change clinical practice and should be considered preliminary. Moreover, the study population was a mixture of patients with hemorrhagic stroke and ischemic stroke, limiting its applicability to either subgroup.
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How should we manage acute hypertension in stroke? Here comes CHIPPS!
April 8, 2008
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