Stopping warfarin in unproved DVT is not easy decision. Identifying patients who are low risk has been a difficult task andi find this study published in Canadian Medical Journal very useful.
It concludes that it may be safe for women who have taken oral anticoagulants for 5–7 months after an unprovoked venous thromboembolism to discontinue therapy if they have 0 or 1 of the following signs or symptoms: hyperpigmentation, edema or redness of either leg; a D-dimer level of 250 µg/L or more while taking warfarin; BMI 30 kg/m2 or more; and age 65 years or more.. What about men?it appears that all men are at high risk of recurrence, particularly men with hyperpigmentation, edema or redness in either leg.They found that men had more than twice the risk of recurrence compared with women and that no subgroup of men with a low risk of recurrence could be identified. Read more..
It concludes that it may be safe for women who have taken oral anticoagulants for 5–7 months after an unprovoked venous thromboembolism to discontinue therapy if they have 0 or 1 of the following signs or symptoms: hyperpigmentation, edema or redness of either leg; a D-dimer level of 250 µg/L or more while taking warfarin; BMI 30 kg/m2 or more; and age 65 years or more.. What about men?it appears that all men are at high risk of recurrence, particularly men with hyperpigmentation, edema or redness in either leg.They found that men had more than twice the risk of recurrence compared with women and that no subgroup of men with a low risk of recurrence could be identified. Read more..
Stopping anticoagulant therapy after an unprovoked venous thromboembolism
ACP guidelines
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