Nearly 20 years ago, it was suggested that individuals exist who are not obese on the basis of height and weight, but who, like people with overt obesity, are hyperinsulinemic, insulin-resistant, and predisposed to type 2 diabetes, hypertriglyceridemia, and premature coronary heart disease. Since then it has become increasingly clear that such metabolically obese, normal-weight (MONW) individuals are very common in the general population and that they probably represent one end of the spectrum of people with the insulin resistance syndrome. Read more..
The opposite may be true as well when obese people are metabolically healthy..Recent publication in Arch. Internal Medicine describes two different phenotypes..
Another study in the same issue of Arch.Internal Medicine concludes that metabolically benign obesity that is not accompanied by insulin resistance and early atherosclerosis exists in humans. Furthermore, ectopic fat in the liver may be more important than visceral fat in the determination of such a beneficial phenotype in obesity.
The opposite may be true as well when obese people are metabolically healthy..Recent publication in Arch. Internal Medicine describes two different phenotypes..
Another study in the same issue of Arch.Internal Medicine concludes that metabolically benign obesity that is not accompanied by insulin resistance and early atherosclerosis exists in humans. Furthermore, ectopic fat in the liver may be more important than visceral fat in the determination of such a beneficial phenotype in obesity.
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