The <>UCSD Statin study yielded further evidence that statin treatment reduces blood pressure (although not by much) The RCT enrolled over 900 subjects without known CVD or diabetes. The idea was to independently assess the effect on BP. There was no inclusion / exclusion criteria regarding baseline BP. Subjects were randomized to pravastatin, simvastatin, or placebo.
Treatment with a statin resulted in about a 2-2.5 point drop in SBP and DBP. The treatment was stopped at 6 months, and the blood pressures returned to baseline by month 8 - further suggesting that this was a true effect.
Beatrice A. Golomb; Joel E. Dimsdale; Halbert L. White; Janis B. Ritchie; Michael H. Criqui
Reduction in Blood Pressure With Statins: Results From the UCSD Statin Study, a Randomized Trial
Arch Intern Med. 2008;168(7):721-727.
Treatment with a statin resulted in about a 2-2.5 point drop in SBP and DBP. The treatment was stopped at 6 months, and the blood pressures returned to baseline by month 8 - further suggesting that this was a true effect.
Beatrice A. Golomb; Joel E. Dimsdale; Halbert L. White; Janis B. Ritchie; Michael H. Criqui
Reduction in Blood Pressure With Statins: Results From the UCSD Statin Study, a Randomized Trial
Arch Intern Med. 2008;168(7):721-727.
