Acute interstitial Nephritis and Steroid Therapy

Acute interstitial nephritis (AIN) is a drug induced renal failure.The culprit was usually an antibiotic:
Antibiotic in 34 cases
Cephalosporin in 15 cases
Quinolone in 12 cases
Penicillin in 7 cases
NSAID in 23 cases
Allopurinol in 1 case
Ranitidine in 1 case
Omeprazole in 1 case
Pimozide in 1 case
Only 8 patients (13%) had the classic triad of fever, rash and eosinophilia
Patients classically have fever, rash and eosinophilia. Read the original article here..