Self-Treatment of Presumptive Malaria in a Traveler
Recommended self treatment regimens
Chloroquine-sensitive regions
(A) Patients not receiving chloroquine prophylaxis
Chloroquine base 600 mg followed by 300 mg base after 6 hours, then 300 mg base daily x 2 days. Children: 10 mg base/kg followed by 5 mg base/kg after 6 hours, then 5 mg base/kg daily x 2 days (maximum are the adult doses).
Start chloroquine prophylaxis.
(B) Patients already receiving chloroquine prophylaxis
Atovaquone/proguanil 1000/400 mg (4 tablets) once daily x 3 days. Children: Atovaquone 20 mg/kg and proguanil 8 mg/kg daily x 3 days (maximum is the adult dose).
Resume chloroquine prophylaxis.
Chloroquine- or chloroquine + mefloquine-resistant P. falciparum regions
(A) Patients not receiving atovaquone/proguanil prophylaxis
Atovaquone/proguanil 1000/400 mg (4 tablets) once daily x 3 days. Children: Atovaquone 20 mg/kg and proguanil 8 mg/kg daily x 3 days (maximum is the adult dose), OR
Quinine/doxycycline: Quinine 250 mg base, 2 tablets three times daily x 7 days, and doxycyline 100 mg twice daily x 7 days.
Start/resume atovaquone/proguanil, doxycycline, or mefloquine.
(B) Patients receiving atovaquone/proguanil prophylaxis
Quinine/doxycycline: Quinine 250 mg base, 2 tablets three times daily x 7 days, and doxycyline 100 mg twice daily x 7 days.
Resume atovaquone/proguanil.
