Users and prescribers of these two supplements take heed. The Glucosamine/chondroitin Arthritis Intervention Trial (GAIT), which followed about 570 patients with osteoarthritis of the knee for two years, has found that none of the treatment groups showed a significant benefit in influencing progressive loss of joint space.
Ref: Sawitzke AD et al. The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: A report from the Glucosamine/chondroitin Arthritis Intervention Trial. Arthritis & Rheumatism 58:3183-3191, 2008
Ref: Sawitzke AD et al. The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: A report from the Glucosamine/chondroitin Arthritis Intervention Trial. Arthritis & Rheumatism 58:3183-3191, 2008
